| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 06/07/2020 | Protalix BioTherapeutics, Inc. | PLX | Grant | Stock Options (Right to Buy) | 197k | $3.59 | $707.2k | | 06/07/2020 |
| 09/13/2018 | Protalix BioTherapeutics, Inc. | PLX | Grant | Stock Options (Right to Buy) | 700k | $0.56 | $392k | | 09/13/2018 |
| 05/02/2012 | Protalix BioTherapeutics, Inc. | PLX | Exercise | Stock Options (Right to Buy) | 50k | $2.65 | $132.5k | | 05/02/2012 |
| 05/02/2012 | Protalix BioTherapeutics, Inc. | PLX | Exercise | Stock Options (Right to Buy) | 116.8k | $0.97 | $113.6k | | 05/02/2012 |
| 05/02/2012 | Protalix BioTherapeutics, Inc. | PLX | Sale | Common Stock | 166.8k | $7.13 | $1.2M | By trust | 05/02/2012 |
| 05/02/2012 | Protalix BioTherapeutics, Inc. | PLX | Exercise | Common Stock | 50k | $2.65 | $132.5k | By trust | 05/02/2012 |
| 05/02/2012 | Protalix BioTherapeutics, Inc. | PLX | Exercise | Common Stock | 116.8k | $0.97 | $113.6k | By trust | 05/02/2012 |
| 09/07/2010 | Protalix BioTherapeutics, Inc. | PLX | Sale | Common Stock | 22.5k | $8.16 | $183.6k | By trust | 09/03/2010 |
| 09/07/2010 | Protalix BioTherapeutics, Inc. | PLX | Exercise | Common Stock | 4.7k | $0.40 | $1.9k | By trust | 09/03/2010 |
| 09/07/2010 | Protalix BioTherapeutics, Inc. | PLX | Exercise | Common Stock | 45.3k | $0.97 | $44k | By trust | 09/03/2010 |
| 09/07/2010 | Protalix BioTherapeutics, Inc. | PLX | Exercise | Stock Options (Right to Buy) | 4.7k | $0.40 | $1.9k | | 09/03/2010 |
| 09/07/2010 | Protalix BioTherapeutics, Inc. | PLX | Exercise | Stock Options (Right to Buy) | 45.3k | $0.97 | $44k | | 09/03/2010 |
| 09/03/2010 | Protalix BioTherapeutics, Inc. | PLX | Sale | Common Stock | 27.5k | $8.00 | $220k | By trust | 09/03/2010 |
| 02/25/2010 | Protalix BioTherapeutics, Inc. | PLX | Grant | Stock Options (Right to Buy) | 130k | $6.90 | $897k | | 02/25/2010 |