| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 10/11/2022 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Restricted Stock Units | 45k | $0.00 | $0 | | 10/11/2022 |
| 02/17/2021 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Stock Option (right to buy) | 94k | $11.41 | $1.1M | | 02/17/2021 |
| 02/13/2020 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Stock Option (right to buy) | 94k | $7.54 | $708.8k | | 02/13/2020 |
| 02/12/2019 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Stock Option (right to buy) | 75k | $6.71 | $503.2k | | 02/12/2019 |
| 02/12/2019 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Common Stock | 87k | $0.00 | $0 | | 02/12/2019 |
| 02/16/2018 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Stock Option (right to buy) | 11.7k | $13.30 | $155.2k | | 02/16/2018 |
| 02/16/2018 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Stock Option (right to buy) | 75k | $10.09 | $756.8k | | 02/16/2018 |
| 02/10/2017 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Stock Option (right to buy) | 40k | $10.90 | $436k | | 02/10/2017 |
| 09/27/2016 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Stock Option (right to buy) | 105k | $13.30 | $1.4M | | 09/27/2016 |
| 09/27/2016 | Syros Pharmaceuticals, Inc. | SYRS | Grant | Stock Option (right to buy) | 35k | $13.30 | $465.5k | | 09/27/2016 |