| Date | Name | Title | Type | Security | Shares | Price | Value | Ownership | Reported |
| 10/04/2023 | DEC TIMOTHY C | Senior Vice-President & CFO | Grant | Performance Share Unit | 4k | $0.00 | $0 | | 10/04/2023 |
| 08/23/2023 | Bhatt Padmanabh P. | Sr. VP of IP, CSO | Grant | Performance Share Unit | 2.5k | $0.00 | $0 | | 08/23/2023 |
| 08/23/2023 | Khattar Jack A. | President, CEO | Grant | Performance Share Unit | 35k | $0.00 | $0 | | 08/23/2023 |
| 08/17/2023 | Sensenig Bethany | Director | Grant | Director Stock Option (Right to Buy) | 24.2k | $30.22 | $729.9k | | 08/17/2023 |
| 05/11/2023 | Khattar Jack A. | President, CEO | Exercise | Performance Share Unit | 31.2k | $0.00 | $0 | | 05/11/2023 |
| 05/11/2023 | Khattar Jack A. | President, CEO | Payment of Exercise | Common Stock | 15k | $36.47 | $547.2k | | 05/11/2023 |
| 05/11/2023 | Bhatt Padmanabh P. | Sr. VP of IP, CSO | Exercise | Performance Share Unit | 750 | $0.00 | $0 | | 05/11/2023 |
| 05/11/2023 | DEC TIMOTHY C | Senior Vice-President & CFO | Payment of Exercise | Common Stock | 709 | $36.47 | $25.9k | | 05/11/2023 |
| 05/11/2023 | DEC TIMOTHY C | Senior Vice-President & CFO | Exercise | Performance Share Units | 1.5k | $0.00 | $0 | | 05/11/2023 |
| 05/04/2023 | DEC TIMOTHY C | Senior Vice-President & CFO | Grant | Performance Share Units | 1.5k | $0.00 | $0 | | 05/04/2023 |
| 05/04/2023 | Bhatt Padmanabh P. | Sr. VP of IP, CSO | Grant | Performance Share Unit | 750 | $0.00 | $0 | | 05/04/2023 |
| 05/04/2023 | Khattar Jack A. | President, CEO | Grant | Performance Share Unit | 31.2k | $0.00 | $0 | | 05/04/2023 |
| 03/14/2023 | Mottola Frank | Sr VP, Quality, GMP Oper. & IT | Sale | Common Stock | 4.8k | $35.99 | $172k | | 03/14/2023 |
| 02/23/2023 | Mottola Frank | Sr VP, Quality, GMP Oper. & IT | Grant | Employee Stock Option (Right to Buy) | 30k | $38.60 | $1.2M | | 02/23/2023 |
| 02/23/2023 | Mottola Frank | Sr VP, Quality, GMP Oper. & IT | Grant | Restricted Stock Units | 7.5k | $0.00 | $0 | | 02/23/2023 |
| 02/23/2023 | Rubin Jonathan | SVP, Chief Medical Officer | Grant | Restricted Stock Units | 5k | $0.00 | $0 | | 02/23/2023 |
| 02/23/2023 | Rubin Jonathan | SVP, Chief Medical Officer | Grant | Employee Stock Option (Right to Buy) | 20k | $38.60 | $772k | | 02/23/2023 |
| 02/23/2023 | Barlow Carrolee | Director | Grant | Director Stock Option (Right to Buy) | 6.3k | $38.60 | $242.9k | | 02/23/2023 |
| 02/23/2023 | Barlow Carrolee | Director | Grant | Restricted Stock Units | 3.9k | $0.00 | $0 | | 02/23/2023 |
| 02/23/2023 | Martin Tami Tillotson | Sr. V.P., Regulatory Affairs | Grant | Employee Stock Option (Right to Buy) | 20k | $38.60 | $772k | | 02/23/2023 |
| 02/23/2023 | Martin Tami Tillotson | Sr. V.P., Regulatory Affairs | Grant | Restricted Stock Units | 5k | $0.00 | $0 | | 02/23/2023 |
| 02/23/2023 | Khattar Jack A. | President, CEO | Grant | Employee Stock Option (Right to Buy) | 280k | $38.60 | $10.8M | | 02/23/2023 |
| 02/23/2023 | Bhatt Padmanabh P. | Sr. VP of IP, CSO | Grant | Restricted Stock Units | 5k | $0.00 | $0 | | 02/23/2023 |
| 02/23/2023 | Bhatt Padmanabh P. | Sr. VP of IP, CSO | Grant | Employee Stock Option (Right to Buy) | 20k | $38.60 | $772k | | 02/23/2023 |
| 02/23/2023 | DEC TIMOTHY C | Senior Vice-President & CFO | Grant | Employee Stock Option (Right to Buy) | 40k | $38.60 | $1.5M | | 02/23/2023 |
| 02/23/2023 | DEC TIMOTHY C | Senior Vice-President & CFO | Grant | Restricted Stock Units | 10k | $0.00 | $0 | | 02/23/2023 |
| 02/23/2023 | GEMAYEL GEORGES | Director | Grant | Director Stock Option (Right to Buy) | 6.3k | $38.60 | $242.9k | | 02/23/2023 |
| 02/23/2023 | GEMAYEL GEORGES | Director | Grant | Restricted Stock Units | 3.9k | $0.00 | $0 | | 02/23/2023 |
| 02/23/2023 | NEWHALL CHARLES W III | Director | Grant | Director Stock Option (Right to Buy) | 6.3k | $38.60 | $242.9k | | 02/23/2023 |
| 02/23/2023 | NEWHALL CHARLES W III | Director | Grant | Restricted Stock Units | 3.9k | $0.00 | $0 | | 02/23/2023 |
| 02/23/2023 | Hudson Frederick M. | Director | Grant | Director Stock Option (Right to Buy) | 6.3k | $38.60 | $242.9k | | 02/23/2023 |
| 02/23/2023 | Hudson Frederick M. | Director | Grant | Restricted Stock Units | 3.9k | $0.00 | $0 | | 02/23/2023 |
| 02/23/2023 | SIEBERT JOHN M | Director | Grant | Director Stock Option (Right to Buy) | 6.3k | $38.60 | $242.9k | | 02/23/2023 |
| 02/23/2023 | SIEBERT JOHN M | Director | Grant | Restricted Stock Units | 3.9k | $0.00 | $0 | | 02/23/2023 |
| 02/22/2023 | SIEBERT JOHN M | Director | Grant | Common Stock | 3.9k | $0.00 | $0 | | 02/22/2023 |
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