| Date | Name | Title | Type | Security | Shares | Price | Value | Ownership | Reported |
| 11/18/2015 | BRIDGER MANAGEMENT, LLC | 10% Owner | Disposition | Common Stock, $0.01 par value per share | 1.8M | $0.00 | $0 | See footnotes | 11/18/2015 |
| 11/18/2015 | BRIDGER MANAGEMENT, LLC | 10% Owner | Disposition | Common Stock, $0.01 par value per share | 2.8M | $0.00 | $0 | See footnotes | 11/18/2015 |
| 11/17/2015 | BRIDGER MANAGEMENT, LLC | 10% Owner | Disposition | Common Stock, $0.01 par value per share | 147.1k | $0.00 | $0 | See footnotes | 11/13/2015 |
| 11/17/2015 | BRIDGER MANAGEMENT, LLC | 10% Owner | Disposition | Common Stock, $0.01 par value per share | 232.9k | $0.00 | $0 | See footnotes | 11/13/2015 |
| 11/16/2015 | BRIDGER MANAGEMENT, LLC | 10% Owner | Disposition | Common Stock, $0.01 par value per share | 116.1k | $0.00 | $0 | See footnotes | 11/13/2015 |
| 11/16/2015 | BRIDGER MANAGEMENT, LLC | 10% Owner | Disposition | Common Stock, $0.01 par value per share | 183.9k | $0.00 | $0 | See footnotes | 11/13/2015 |
| 11/13/2015 | BRIDGER MANAGEMENT, LLC | 10% Owner | Disposition | Common Stock, $0.01 par value per share | 547.1k | $0.00 | $0 | See footnotes | 11/13/2015 |
| 11/13/2015 | BRIDGER MANAGEMENT, LLC | 10% Owner | Disposition | Common Stock, $0.01 par value per share | 47.9k | $0.00 | $0 | See footnotes | 11/13/2015 |
| 11/11/2015 | BRIDGER MANAGEMENT, LLC | 10% Owner | Disposition | Common Stock, $0.01 par value per share | 30k | $0.00 | $0 | See footnotes | 11/10/2015 |
| 11/10/2015 | BRIDGER MANAGEMENT, LLC | 10% Owner | Disposition | Common Stock, $0.01 par value per share | 60k | $0.00 | $0 | See footnotes | 11/10/2015 |
| 04/03/2015 | BRIDGER MANAGEMENT, LLC | 10% Owner | Other (acquisition) | Warrants (right to buy) | 1.4M | $0.37 | $500k | See footnotes | 04/03/2015 |
| 07/10/2014 | Serruya Michael | Director | Grant | Stock Option (right to buy) | 27k | $0.88 | $23.8k | | 07/10/2014 |
| 07/10/2014 | HARRIS KEVIN ROY | Vice President and CFO | Grant | Stock Option (right to buy) | 45k | $0.88 | $39.6k | | 07/10/2014 |
| 07/10/2014 | van den Broek Richard | Director | Grant | Stock Option (right to buy) | 27k | $0.88 | $23.8k | | 07/10/2014 |
| 07/10/2014 | BOLOGNA THOMAS A | CEO | Grant | Stock Option (right to buy) | 200k | $0.88 | $176k | | 07/10/2014 |
| 07/10/2014 | CALHOUN KIRK K | Director | Grant | Stock Option (right to buy) | 33.8k | $0.88 | $29.7k | | 07/10/2014 |
| 07/10/2014 | WURZER DAVID M | Director | Grant | Stock Option (right to buy) | 27k | $0.88 | $23.8k | | 07/10/2014 |
| 07/10/2014 | ASTROW STEPHANIE H. | VP of Research and Development | Grant | Stock Option (right to buy) | 45k | $0.88 | $39.6k | | 07/10/2014 |
| 07/10/2014 | GETACHEW ADANECH | General Counsel | Grant | Stock Option (right to buy) | 10k | $0.88 | $8.8k | | 07/10/2014 |
| 07/10/2014 | CHAWLA SAM | Director | Grant | Stock Option (right to buy) | 27k | $0.88 | $23.8k | | 07/10/2014 |
| 07/10/2014 | SCHREIBER DAVID | Director | Grant | Stock Option (right to buy) | 27k | $0.88 | $23.8k | | 07/10/2014 |
| 12/23/2013 | MARXE AUSTIN W & GREENHOUSE DAVID M | 10% Owner | Sale | Common Stock | 128.3k | $1.11 | $142.4k | By Limited Partnerships | 12/20/2013 |
| 12/20/2013 | MARXE AUSTIN W & GREENHOUSE DAVID M | 10% Owner | Sale | Common Stock | 6.7k | $1.17 | $7.8k | By Limited Partnerships | 12/20/2013 |
| 12/19/2013 | MARXE AUSTIN W & GREENHOUSE DAVID M | 10% Owner | Sale | Common Stock | 17.4k | $1.17 | $20.4k | By Limited Partnerships | 12/18/2013 |
| 12/18/2013 | MARXE AUSTIN W & GREENHOUSE DAVID M | 10% Owner | Sale | Common Stock | 118.2k | $1.18 | $139.1k | By Limited Partnerships | 12/18/2013 |
| 12/16/2013 | MARXE AUSTIN W & GREENHOUSE DAVID M | 10% Owner | Sale | Common Stock | 3.7k | $1.15 | $4.2k | By Limited Partnerships | 12/13/2013 |
| 12/13/2013 | MARXE AUSTIN W & GREENHOUSE DAVID M | 10% Owner | Sale | Common Stock | 350k | $1.17 | $408.7k | By Limited Partnerships | 12/13/2013 |
| 11/20/2013 | van den Broek Richard | Director | Grant | Stock Option (right to buy) | 27k | $1.31 | $35.4k | | 11/20/2013 |
| 11/20/2013 | Serruya Michael | Director | Grant | Stock Option (right to buy) | 27k | $1.31 | $35.4k | | 11/20/2013 |
| 11/20/2013 | WURZER DAVID M | Director | Grant | Stock Option (right to buy) | 27k | $1.31 | $35.4k | | 11/20/2013 |
| 11/20/2013 | CALHOUN KIRK K | Director | Grant | Stock Option (right to buy) | 33.8k | $1.31 | $44.2k | | 11/20/2013 |
| 11/20/2013 | BOLOGNA THOMAS A | CEO | Grant | Stock Option (right to buy) | 232k | $1.31 | $303.9k | | 11/20/2013 |
| 11/20/2013 | HARRIS KEVIN ROY | Vice President and CFO | Grant | Stock Option (right to buy) | 48k | $1.31 | $62.9k | | 11/20/2013 |
| 11/20/2013 | ASTROW STEPHANIE H. | VP of Research and Development | Grant | Stock Option (right to buy) | 50k | $1.31 | $65.5k | | 11/20/2013 |
| 11/20/2013 | CHAWLA SAM | Director | Grant | Stock Option (right to buy) | 54k | $1.31 | $70.7k | | 11/20/2013 |
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