| Date | Name | Title | Type | Security | Shares | Price | Value | Ownership | Reported |
| 10/04/2023 | Madryn Asset Management, LP | 10% Owner | Purchase | Secured Subordinated Convertible Notes | 0 | $0.00 | $0 | See footnotes | 10/04/2023 |
| 10/04/2023 | Madryn Asset Management, LP | 10% Owner | Disposition | Secured Subordinated Convertible Notes | 0 | $0.00 | $0 | See footnotes | 10/04/2023 |
| 10/04/2023 | Madryn Asset Management, LP | 10% Owner | Purchase | Series X Convertible Preferred Stock | 248.8k | $0.00 | $0 | See footnotes | 10/04/2023 |
| 08/11/2023 | MANDARELLO MICHAEL | General Counsel & Secretary | Grant | Common Stock | 834 | $0.00 | $0 | | 08/11/2023 |
| 08/11/2023 | MANDARELLO MICHAEL | General Counsel & Secretary | Payment of Exercise | Common Stock | 233 | $0.00 | $0 | | 08/11/2023 |
| 07/12/2023 | EW Healthcare Partners, L.P. | 10% Owner | Purchase | Senior Convertible Preferred Stock | 500k | $4.00 | $2M | I | 07/12/2023 |
| 05/15/2023 | EW Healthcare Partners, L.P. | 10% Owner | Purchase | Senior Convertible Preferred Stock | 280.9k | $0.00 | $0 | I | 05/15/2023 |
| 11/29/2022 | Natale Anthony | Director | Sale | Common Shares | 51.4k | $0.24 | $12.5k | By Partnership | 11/28/2022 |
| 11/28/2022 | Natale Anthony | Director | Sale | Common Shares | 51.4k | $0.27 | $13.7k | By Partnership | 11/28/2022 |
| 11/25/2022 | Natale Anthony | Director | Sale | Common Shares | 51.4k | $0.31 | $15.8k | By Partnership | 11/22/2022 |
| 11/23/2022 | Natale Anthony | Director | Sale | Common Shares | 51.4k | $0.33 | $17k | By Partnership | 11/22/2022 |
| 11/22/2022 | Natale Anthony | Director | Sale | Common Shares | 51.4k | $0.20 | $10.1k | By Partnership | 11/22/2022 |
| 11/21/2022 | PORTARO ROSS | President Global Sales | Purchase | Common Shares | 60k | $0.22 | $13.2k | | 11/21/2022 |
| 11/18/2022 | HOLLMIG STANLEY TYLER | Director | Purchase | Common Stock | 250k | $0.20 | $50k | | 11/18/2022 |
| 11/18/2022 | HealthQuest Partners II, L.P. | 10% Owner | Purchase | Voting Convertible Preferred Stock | 335k | $2.00 | $670k | | 11/18/2022 |
| 11/18/2022 | EW Healthcare Partners, L.P. | 10% Owner | Purchase | Voting Convertible Preferred Stock | 1.4M | $2.00 | $2.9M | EW Healthcare Partners, LP | 11/18/2022 |
| 11/18/2022 | EW Healthcare Partners, L.P. | 10% Owner | Purchase | Voting Convertible Preferred Stock | 58k | $2.00 | $116k | EW Healthcare Partners-A, LP | 11/18/2022 |
| 11/18/2022 | EW Healthcare Partners, L.P. | 10% Owner | Purchase | Voting Convertible Preferred Stock | 1.4M | $2.00 | $2.9M | EW Healthcare Partners, LP | 11/18/2022 |
| 11/18/2022 | EW Healthcare Partners, L.P. | 10% Owner | Purchase | Voting Convertible Preferred Stock | 58k | $2.00 | $116k | EW Healthcare Partners-A, LP | 11/18/2022 |
| 11/18/2022 | Kong Garheng | 10% Owner | Purchase | Voting Convertible Preferred Stock | 335k | $2.00 | $670k | HealthQuest Partners II, L.P. | 11/18/2022 |
| 11/18/2022 | Varghese Hemanth Jacob | President/Chief Bus. Officer | Purchase | Common Stock | 250k | $0.20 | $50k | | 11/18/2022 |
| 11/18/2022 | DE SILVA RAJIV | Officer | Purchase | Common Stock | 1.2M | $0.20 | $250k | | 11/18/2022 |
| 11/18/2022 | BARRY RICHARD SCOTT | 10% Owner | Purchase | Voting Convertible Preferred Stock | 1.4M | $2.00 | $2.9M | EW Healthcare Partners, LP | 11/18/2022 |
| 11/18/2022 | BARRY RICHARD SCOTT | 10% Owner | Purchase | Voting Convertible Preferred Stock | 58k | $2.00 | $116k | Held by EW Healthcare Partners-A.L.P. | 11/18/2022 |
| 11/10/2022 | Della Penna Domenic | CFO | Grant | Employee Stock Option (Right to Buy) | 250k | $0.21 | $52.5k | | 11/10/2022 |
| 11/10/2022 | Iger Yoni | VP, RA/QA/Clinical Affairs | Grant | Employee Stock Option (Right to Buy) | 50k | $0.21 | $10.5k | | 11/10/2022 |
| 11/10/2022 | Sinay Soren Maor | COO | Grant | Employee Stock Option (Right to Buy) | 150k | $0.21 | $31.5k | | 11/10/2022 |
| 11/10/2022 | Georgiadis Anna | VP, Global HR | Grant | Employee Stock Option (Right to Buy) | 100k | $0.21 | $21k | | 11/10/2022 |
| 11/10/2022 | MCGRAIL WILLIAM H | VP Regulatory Affairs | Grant | Employee Stock Option (Right to Buy) | 100k | $0.21 | $21k | | 11/10/2022 |
| 11/10/2022 | KOTLER ANAT | Interim VP, Global Marketing | Grant | Employee Stock Option (Right to Buy) | 75k | $0.21 | $15.8k | | 11/10/2022 |
| 11/10/2022 | PORTARO ROSS | President Global Sales | Grant | Employee Stock Option (Right to Buy) | 100k | $0.21 | $21k | | 11/10/2022 |
| 11/10/2022 | MANDARELLO MICHAEL | General Counsel & Secretary | Grant | Employee Stock Option (Right to Buy) | 100k | $0.21 | $21k | | 11/10/2022 |
| 11/10/2022 | SHIMIZU KENJI | Interim CTO | Grant | Employee Stock Option (Right to Buy) | 25k | $0.21 | $5.2k | | 11/10/2022 |
| 10/17/2022 | Varghese Hemanth Jacob | President/Chief Bus. Officer | Grant | Employee Stock Option (Right to Buy) | 1.1M | $0.27 | $299.8k | | 10/17/2022 |
| 10/02/2022 | DE SILVA RAJIV | Officer | Grant | Employee Stock Option (Right to Buy) | 3.3M | $0.44 | $1.5M | | 10/02/2022 |
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