| Date | Name | Title | Type | Security | Shares | Price | Value | Ownership | Reported |
| 01/05/2023 | Keran Patrick L | SVP, General Counsel | Disposition | Employee Stock Option (Right to Buy) | 60k | $15.08 | $904.8k | | 01/05/2023 |
| 01/05/2023 | Cirino Dennis | SVP, Global Spinal Systems | Disposition | Common Stock | 48.6k | $0.00 | $0 | | 01/05/2023 |
| 01/05/2023 | Cirino Dennis | SVP, Global Spinal Systems | Disposition | Restricted Stock Units | 11.8k | $0.00 | $0 | | 01/05/2023 |
| 01/05/2023 | Cirino Dennis | SVP, Global Spinal Systems | Disposition | Restricted Stock Units | 16.5k | $0.00 | $0 | | 01/05/2023 |
| 01/05/2023 | Cirino Dennis | SVP, Global Spinal Systems | Disposition | Employee Stock Option (Right to Buy) | 34.2k | $18.24 | $624k | | 01/05/2023 |
| 01/05/2023 | Cirino Dennis | SVP, Global Spinal Systems | Disposition | Employee Stock Option (Right to Buy) | 53.5k | $12.01 | $642.8k | | 01/05/2023 |
| 01/05/2023 | Cirino Dennis | SVP, Global Spinal Systems | Disposition | Employee Stock Option (Right to Buy) | 5.8k | $9.93 | $58k | | 01/05/2023 |
| 01/05/2023 | Cirino Dennis | SVP, Global Spinal Systems | Disposition | Employee Stock Option (Right to Buy) | 19.7k | $16.86 | $331.3k | | 01/05/2023 |
| 01/05/2023 | Cirino Dennis | SVP, Global Spinal Systems | Disposition | Employee Stock Option (Right to Buy) | 41.2k | $12.67 | $522.4k | | 01/05/2023 |
| 01/05/2023 | Cirino Dennis | SVP, Global Spinal Systems | Disposition | Employee Stock Option (Right to Buy) | 20.6k | $12.67 | $261.2k | | 01/05/2023 |
| 01/05/2023 | Benny Paul S. | VP, Treasurer | Disposition | Common Stock | 21k | $0.00 | $0 | | 01/05/2023 |
| 01/05/2023 | Benny Paul S. | VP, Treasurer | Disposition | Restricted Stock Units | 1.2k | $0.00 | $0 | | 01/05/2023 |
| 01/05/2023 | Benny Paul S. | VP, Treasurer | Disposition | Restricted Stock Units | 2.8k | $0.00 | $0 | | 01/05/2023 |
| 01/05/2023 | Benny Paul S. | VP, Treasurer | Disposition | Employee Stock Option (Right to Buy) | 10k | $15.68 | $156.8k | | 01/05/2023 |
| 01/05/2023 | Benny Paul S. | VP, Treasurer | Disposition | Employee Stock Option (Right to Buy) | 8.8k | $14.19 | $124.9k | | 01/05/2023 |
| 01/05/2023 | Benny Paul S. | VP, Treasurer | Disposition | Employee Stock Option (Right to Buy) | 3.4k | $18.24 | $62.4k | | 01/05/2023 |
| 01/05/2023 | Benny Paul S. | VP, Treasurer | Disposition | Employee Stock Option (Right to Buy) | 10.4k | $12.01 | $124.9k | | 01/05/2023 |
| 01/05/2023 | Keran Patrick L | SVP, General Counsel | Disposition | Employee Stock Option (Right to Buy) | 64.6k | $14.19 | $916.7k | | 01/05/2023 |
| 01/05/2023 | Keran Patrick L | SVP, General Counsel | Disposition | Employee Stock Option (Right to Buy) | 33.7k | $18.24 | $615.6k | | 01/05/2023 |
| 01/05/2023 | Keran Patrick L | SVP, General Counsel | Disposition | Employee Stock Option (Right to Buy) | 52.8k | $12.01 | $634.1k | | 01/05/2023 |
| 01/05/2023 | Keran Patrick L | SVP, General Counsel | Disposition | Employee Stock Option (Right to Buy) | 6k | $9.93 | $60k | | 01/05/2023 |
| 01/05/2023 | Keran Patrick L | SVP, General Counsel | Disposition | Employee Stock Option (Right to Buy) | 40.8k | $16.86 | $687.7k | | 01/05/2023 |
| 01/05/2023 | Lipschultz Tyler | SVP, Orthobiologics and BD | Disposition | Employee Stock Option (Right to Buy) | 21.2k | $15.00 | $318.5k | | 01/05/2023 |
| 01/05/2023 | Keran Patrick L | SVP, General Counsel | Disposition | Common Stock | 69.6k | $0.00 | $0 | | 01/05/2023 |
| 01/05/2023 | Keran Patrick L | SVP, General Counsel | Disposition | Restricted Stock Units | 8.2k | $0.00 | $0 | | 01/05/2023 |
| 01/05/2023 | Keran Patrick L | SVP, General Counsel | Disposition | Restricted Stock Units | 52.1k | $0.00 | $0 | | 01/05/2023 |
| 01/05/2023 | Keran Patrick L | SVP, General Counsel | Disposition | Employee Stock Option (Right to Buy) | 21.7k | $15.00 | $325.6k | | 01/05/2023 |
| 01/05/2023 | Benny Paul S. | VP, Treasurer | Disposition | Employee Stock Option (Right to Buy) | 2.7k | $9.93 | $27k | | 01/05/2023 |
| 01/05/2023 | Benny Paul S. | VP, Treasurer | Disposition | Employee Stock Option (Right to Buy) | 5.9k | $16.86 | $99.9k | | 01/05/2023 |
| 01/05/2023 | Benny Paul S. | VP, Treasurer | Disposition | Employee Stock Option (Right to Buy) | 6.9k | $12.67 | $87.5k | | 01/05/2023 |
| 01/05/2023 | Bostjancic John J. | CFO | Disposition | Common Stock | 102.6k | $0.00 | $0 | | 01/05/2023 |
| 01/05/2023 | Bostjancic John J. | CFO | Disposition | Restricted Stock Units | 13.8k | $0.00 | $0 | | 01/05/2023 |
| 01/05/2023 | Bostjancic John J. | CFO | Disposition | Restricted Stock Units | 51.8k | $0.00 | $0 | | 01/05/2023 |
| 01/05/2023 | Bostjancic John J. | CFO | Disposition | Employee Stock Option (Right to Buy) | 62k | $15.68 | $972.2k | | 01/05/2023 |
| 01/05/2023 | Bostjancic John J. | CFO | Disposition | Employee Stock Option (Right to Buy) | 64.6k | $14.19 | $916.7k | | 01/05/2023 |
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