| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 01/11/2023 | Imago BioSciences, Inc. | IMGO | Disposition | Stock Option (Right to Buy) | 11.9k | $15.65 | $186.3k | | 01/11/2023 |
| 01/11/2023 | Imago BioSciences, Inc. | IMGO | Disposition | Stock Option (Right to Buy) | 23.8k | $22.76 | $541.9k | | 01/11/2023 |
| 06/21/2022 | Immuneering Corp | IMRX | Grant | Stock Option | 14.2k | $4.63 | $65.7k | | 06/21/2022 |
| 06/01/2022 | Imago BioSciences, Inc. | IMGO | Grant | Stock Option (Right to Buy) | 11.9k | $15.65 | $186.3k | | 06/01/2022 |
| 05/16/2022 | Immuneering Corp | IMRX | Purchase | Class A Common Stock | 7k | $5.00 | $35k | | 05/16/2022 |
| 05/06/2022 | PepGen Inc. | | Purchase | Common Stock | 4.2k | $12.00 | $50k | | 05/06/2022 |
| 05/06/2022 | PepGen Inc. | | Grant | Stock Option (Right to Buy) | 5.8k | $12.00 | $70k | | 05/06/2022 |
| 11/17/2021 | Imago BioSciences, Inc. | IMGO | Grant | Stock Option (Right to Buy) | 23.8k | $22.76 | $541.9k | | 11/17/2021 |
| 08/05/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Performance Stock Option 2015 (right to buy) | 2.1k | $88.95 | $188.9k | | 08/05/2021 |
| 08/05/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (right to buy) | 7.9k | $88.95 | $700.6k | | 08/05/2021 |
| 08/05/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 10k | $188.95 | $1.9M | | 08/05/2021 |
| 08/03/2021 | Immuneering Corp | IMRX | Purchase | Class A Common Stock | 7k | $15.00 | $105k | | 08/03/2021 |
| 07/12/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 1.8k | $179.00 | $324.3k | | 07/12/2021 |
| 07/12/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 5k | $178.95 | $894.8k | | 07/12/2021 |
| 07/12/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (right to buy) | 1.8k | $85.00 | $154k | | 07/12/2021 |
| 07/12/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (right to buy) | 5k | $88.95 | $444.8k | | 07/12/2021 |
| 06/09/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 1.7k | $154.00 | $267k | | 06/09/2021 |
| 04/20/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Payment of Exercise | Common Stock | 2k | $131.75 | $265.3k | | 04/19/2021 |
| 04/20/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Payment of Exercise | Common Stock | 75 | $134.42 | $10.1k | | 04/19/2021 |
| 04/19/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Common Stock | 4.5k | $0.00 | $0 | | 04/19/2021 |
| 02/24/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Stock Option (right to buy) | 17.8k | $151.59 | $2.7M | | 02/24/2021 |
| 02/12/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Payment of Exercise | Common Stock | 1.9k | $156.00 | $289.7k | | 02/11/2021 |
| 02/12/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Payment of Exercise | Common Stock | 106 | $153.54 | $16.3k | | 02/11/2021 |
| 02/11/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Performance Stock Option 2017 (right to buy) | 4.6k | $119.13 | $546.1k | | 02/11/2021 |
| 02/11/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Grant | Common Stock | 4.2k | $0.00 | $0 | | 02/11/2021 |
| 01/13/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 5k | $169.00 | $845k | | 01/13/2021 |
| 01/13/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 3k | $170.00 | $510k | | 01/13/2021 |
| 01/13/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 1k | $174.00 | $178.7k | | 01/13/2021 |
| 01/13/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (right to buy) | 3k | $77.40 | $234.3k | | 01/13/2021 |
| 01/13/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (right to buy) | 6k | $85.00 | $510k | | 01/13/2021 |
| 01/12/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (right to buy) | 13k | $77.40 | $1M | | 01/11/2021 |
| 01/12/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Exercise | Stock Option (right to buy) | 1.9k | $42.22 | $81.9k | | 01/11/2021 |
| 01/12/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 3k | $165.00 | $495k | | 01/11/2021 |
| 01/12/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 11.9k | $159.00 | $1.9M | | 01/11/2021 |
| 01/11/2021 | ALNYLAM PHARMACEUTICALS, INC. | ALNY | Sale | Common Stock | 758 | $154.00 | $116.7k | | 01/11/2021 |
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