| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 10/04/2023 | ACELYRIN, Inc. | | Other (acquisition) | Common Stock | 14.7k | $0.00 | $0 | See footnote | 10/04/2023 |
| 06/15/2023 | Arcus Biosciences, Inc. | RCUS | Grant | Common Stock | 6.8k | $0.00 | $0 | | 06/15/2023 |
| 06/15/2023 | Arcus Biosciences, Inc. | RCUS | Grant | Stock Option (Right to Buy) | 19.5k | $19.60 | $382.2k | | 06/15/2023 |
| 06/09/2023 | CHIMERIX INC | CMRX | Grant | Stock Option (Right to Buy) | 60k | $1.39 | $83.4k | | 06/09/2023 |
| 06/02/2023 | Xenon Pharmaceuticals Inc. | XENE | Grant | Stock Option (Right to Buy) | 18.5k | $38.96 | $719.8k | | 06/02/2023 |
| 05/09/2023 | ACELYRIN, Inc. | | Other (acquisition) | Director Stock Option (right to buy) | 23.2k | $18.00 | $418.4k | | 05/09/2023 |
| 05/09/2023 | ACELYRIN, Inc. | | Other (acquisition) | Director Stock Option (right to buy) | 86.2k | $5.88 | $506.6k | | 05/09/2023 |
| 05/09/2023 | ACELYRIN, Inc. | | Other (disposition) | Director Stock Option (right to buy) | 86.2k | $5.88 | $506.6k | | 05/09/2023 |
| 05/09/2023 | ACELYRIN, Inc. | | Other (acquisition) | Director Stock Option (right to buy) | 40.6k | $0.77 | $31.2k | | 05/09/2023 |
| 05/09/2023 | ACELYRIN, Inc. | | Other (disposition) | Director Stock Option (right to buy) | 40.6k | $0.77 | $31.2k | | 05/09/2023 |
| 05/09/2023 | ACELYRIN, Inc. | | Other (disposition) | Director Stock Option (right to buy) | 23.2k | $18.00 | $418.4k | | 05/09/2023 |
| 05/09/2023 | ACELYRIN, Inc. | | Other (acquisition) | Director Stock Option (right to buy) | 28.7k | $5.88 | $168.5k | | 05/09/2023 |
| 05/09/2023 | ACELYRIN, Inc. | | Other (disposition) | Director Stock Option (right to buy) | 28.7k | $5.88 | $168.5k | | 05/09/2023 |
| 05/04/2023 | ACELYRIN, Inc. | | Grant | Director Stock Option (right to buy) | 23.2k | $18.00 | $418.4k | | 05/04/2023 |
| 08/17/2022 | Turning Point Therapeutics, Inc. | TPTX | Disposition | Stock Option (right to buy) | 30k | $29.56 | $886.8k | | 08/17/2022 |
| 08/17/2022 | Turning Point Therapeutics, Inc. | TPTX | Disposition | Stock Option (right to buy) | 8.5k | $65.39 | $555.8k | | 08/17/2022 |
| 08/17/2022 | Turning Point Therapeutics, Inc. | TPTX | Disposition | Stock Option (right to buy) | 8.5k | $65.64 | $557.9k | | 08/17/2022 |
| 06/28/2022 | Xenon Pharmaceuticals Inc. | XENE | Grant | Stock Option (Right to Buy) | 18k | $30.11 | $542k | | 06/28/2022 |
| 06/23/2022 | CHIMERIX INC | CMRX | Grant | Stock Option (Right to Buy) | 50k | $1.82 | $91k | | 06/23/2022 |
| 06/14/2022 | Arcus Biosciences, Inc. | RCUS | Grant | Common Stock | 4.1k | $0.00 | $0 | | 06/14/2022 |
| 06/14/2022 | Arcus Biosciences, Inc. | RCUS | Grant | Stock Option (Right to Buy) | 16.8k | $20.62 | $346.4k | | 06/14/2022 |
| 06/10/2022 | Adverum Biotechnologies, Inc. | ADVM | Grant | Stock Option (Right to Buy) | 12.5k | $0.99 | $12.4k | | 06/10/2022 |
| 06/10/2022 | Adverum Biotechnologies, Inc. | ADVM | Grant | Stock Option (Right to Buy) | 40k | $0.99 | $39.6k | | 06/10/2022 |
| 06/23/2021 | CHIMERIX INC | CMRX | Grant | Stock Option (Right to Buy) | 35k | $7.84 | $274.4k | | 06/23/2021 |
| 06/03/2021 | Arcus Biosciences, Inc. | RCUS | Grant | Stock Option (Right to Buy) | 14.1k | $24.79 | $349.5k | | 06/03/2021 |
| 06/03/2021 | Arcus Biosciences, Inc. | RCUS | Grant | Common Stock | 3k | $0.00 | $0 | | 06/03/2021 |
| 06/03/2021 | Xenon Pharmaceuticals Inc. | XENE | Grant | Stock Option (Right to Buy) | 10k | $18.56 | $185.6k | | 06/03/2021 |
| 06/02/2021 | Turning Point Therapeutics, Inc. | TPTX | Grant | Stock Option (right to buy) | 8.5k | $65.64 | $557.9k | | 06/02/2021 |
| 05/12/2021 | Adverum Biotechnologies, Inc. | ADVM | Grant | Stock Option (Right to Buy) | 40k | $3.70 | $148k | | 05/12/2021 |
| 05/12/2021 | Adverum Biotechnologies, Inc. | ADVM | Grant | Stock Option (Right to Buy) | 12.5k | $3.70 | $46.2k | | 05/12/2021 |
| 03/24/2021 | Adverum Biotechnologies, Inc. | ADVM | Purchase | Common Stock | 10k | $9.92 | $99.2k | | 03/24/2021 |
| 01/15/2021 | Adverum Biotechnologies, Inc. | ADVM | Purchase | Common Stock | 10k | $11.52 | $115.2k | | 01/15/2021 |
| 11/05/2020 | Xenon Pharmaceuticals Inc. | XENE | Grant | Stock Option (Right to Buy) | 20k | $11.85 | $237k | | 11/05/2020 |
| 09/28/2020 | Principia Biopharma Inc. | PRNB | Disposition | Director Stock Option (right to buy) | 20.5k | $31.77 | $650.5k | | 09/28/2020 |
| 09/28/2020 | Principia Biopharma Inc. | PRNB | Disposition | Director Stock Option (right to buy) | 10.2k | $31.77 | $325.3k | | 09/28/2020 |
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