| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 06/22/2022 | Alaunos Therapeutics, Inc. | ZIOP | Grant | Common Stock | 40k | $0.00 | $0 | | 06/22/2022 |
| 06/22/2022 | Alaunos Therapeutics, Inc. | ZIOP | Grant | Employee Stock Option (right to buy) | 100k | $0.82 | $82k | | 06/22/2022 |
| 06/18/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Sale | Common stock | 48.5k | $60.11 | $2.9M | | 06/18/2021 |
| 06/18/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Stock option (right to buy) | 1.9k | $39.76 | $74.9k | | 06/18/2021 |
| 06/18/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Stock option (right to buy) | 46.6k | $50.40 | $2.3M | | 06/18/2021 |
| 06/17/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Sale | Common stock | 2.5k | $60.02 | $150.2k | | 06/17/2021 |
| 06/17/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Stock option (right to buy) | 2.5k | $39.76 | $99.5k | | 06/17/2021 |
| 06/10/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Stock option (right to buy) | 20.9k | $39.76 | $829.1k | | 06/09/2021 |
| 06/10/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Sale | Common stock | 20.9k | $60.06 | $1.3M | | 06/09/2021 |
| 06/09/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Stock option (right to buy) | 7.1k | $39.76 | $284.2k | | 06/09/2021 |
| 06/09/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Sale | Common stock | 7.1k | $60.16 | $430.1k | | 06/09/2021 |
| 06/08/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Stock option (right to buy) | 6.7k | $39.76 | $265.4k | | 06/07/2021 |
| 06/08/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Sale | Common stock | 6.7k | $60.07 | $400.9k | | 06/07/2021 |
| 06/07/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Stock option (right to buy) | 4.3k | $39.76 | $169.7k | | 06/07/2021 |
| 06/07/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Sale | Common stock | 4.3k | $60.04 | $256.2k | | 06/07/2021 |
| 04/20/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Sale | Common stock | 14.4k | $55.11 | $793.6k | | 04/19/2021 |
| 04/20/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Stock option (right to buy) | 12.5k | $35.16 | $440k | | 04/19/2021 |
| 04/20/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Stock option (right to buy) | 1.9k | $39.76 | $75.1k | | 04/19/2021 |
| 04/19/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Stock option (right to buy) | 3.2k | $35.16 | $112.9k | | 04/19/2021 |
| 04/19/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Sale | Common stock | 3.2k | $55.16 | $177.1k | | 04/19/2021 |
| 03/04/2021 | Alaunos Therapeutics, Inc. | ZIOP | Grant | Common Stock | 4.2k | $0.00 | $0 | | 03/04/2021 |
| 03/04/2021 | Alaunos Therapeutics, Inc. | ZIOP | Grant | Stock Option (right to buy) | 31.2k | $4.31 | $134.7k | | 03/04/2021 |
| 02/24/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Payment of Exercise | Common stock | 986 | $0.00 | $0 | | 02/22/2021 |
| 02/22/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Restricted stock units | 3.3k | $0.00 | $0 | | 02/22/2021 |
| 02/16/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Payment of Exercise | Common stock | 2.1k | $0.00 | $0 | | 02/14/2021 |
| 02/16/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Restricted stock unit | 2.8k | $0.00 | $0 | | 02/14/2021 |
| 02/14/2021 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Restricted stock units | 4k | $0.00 | $0 | | 02/14/2021 |
| 05/21/2020 | Viridian Therapeutics, Inc.\DE | MGEN | Grant | Stock Option (right to buy) | 24k | $0.63 | $15k | | 05/21/2020 |
| 05/20/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | Sale | Common stock | 3.6k | $50.01 | $179.2k | | 05/20/2020 |
| 05/20/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Stock option (right to buy) | 3.6k | $35.16 | $126k | | 05/20/2020 |
| 04/14/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | Payment of Exercise | Common stock | 2.4k | $40.64 | $96.2k | | 04/13/2020 |
| 04/13/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Performance share units | 5.3k | $0.00 | $0 | | 04/13/2020 |
| 02/24/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | Payment of Exercise | Common stock | 1.6k | $48.66 | $77.7k | | 02/22/2020 |
| 02/22/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | Exercise | Restricted stock units | 3.3k | $0.00 | $0 | | 02/22/2020 |
| 02/18/2020 | AGIOS PHARMACEUTICALS, INC. | AGIO | Payment of Exercise | Common stock | 819 | $52.01 | $42.6k | | 02/14/2020 |
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