| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 02/08/2023 | Zynerba Pharmaceuticals, Inc. | ZYNE | Payment of Exercise | Common Stock | 5.1k | $0.60 | $3.1k | | 02/07/2023 |
| 02/07/2023 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 14.9k | $0.00 | $0 | | 02/07/2023 |
| 01/24/2023 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 120k | $0.00 | $0 | | 01/23/2023 |
| 01/23/2023 | Zynerba Pharmaceuticals, Inc. | ZYNE | Sale | Common Stock | 12.7k | $0.60 | $7.6k | | 01/23/2023 |
| 07/19/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Sale | Common Stock | 4.3k | $1.10 | $4.7k | | 07/18/2022 |
| 07/18/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 14.8k | $0.00 | $0 | | 07/18/2022 |
| 01/26/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 90k | $2.41 | $216.9k | | 01/26/2022 |
| 01/26/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 60k | $0.00 | $0 | | 01/26/2022 |
| 01/21/2021 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Common Stock | 37k | $0.00 | $0 | | 01/21/2021 |
| 01/21/2021 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 55k | $3.58 | $196.9k | | 01/21/2021 |
| 01/30/2020 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 10k | $5.05 | $50.5k | | 01/30/2020 |
| 01/30/2020 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 48k | $5.05 | $242.4k | | 01/30/2020 |
| 01/24/2019 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 42.3k | $3.65 | $154.3k | | 01/24/2019 |
| 01/11/2018 | Zynerba Pharmaceuticals, Inc. | ZYNE | Grant | Stock Option (right to buy) | 42k | $11.71 | $491.8k | | 01/11/2018 |