Type	Name	Date
Credit agreement	Amended and Restated Credit Agreement, by and among Alexion Pharmaceuticals, Inc, as administrative borrower, the subsidiary borrowers party thereto, the lenders and other financial institutions party thereto and Bank of America, N.A., as administrative agent	06/13/2018
Credit agreement	Credit Agreement, by and among Alexion Pharmaceuticals, Inc, as administrative borrower, the guarantors referred to therein, the lenders referred to therein and Bank of America, N.A., as administrative agent	06/23/2015
Credit agreement	Credit Agreement by and among Alexion Pharmaceuticals, Inc., certain Subsidiaries of Alexion, the lenders party hereto, Bank of America, N.A., as Administrative Agent, Merrill Lynch, Pierce, Fenner & Smith Incorporated and J.P. Morgan Securities LLC, as joint lead arrangers and joint book managers	02/07/2012
Credit agreement	Second Amended and Restated Credit Agreement, among Alexion, Bank of America, N.A. as administrative agent, the other lenders party thereto, and Merrill Lynch, Pierce, Fenner & Smith Incorporated and J.P. Morgan Securities Inc., as joint lead arrangers	03/10/2011

Type	Name	Date
By-Laws	Amended and Restated Bylaws of Alexion Pharmaceuticals Inc.	07/22/2021
By-Laws	Amended and Restated By-Laws of Alexion Pharmaceuticals, Inc	01/14/2016
By-Laws	Amended and Restated By-Laws	04/17/2014

Type	Name	Date
Merger agreement	AGREEMENT AND PLAN OF MERGER by and among PORTOLA PHARMACEUTICALS, INC., ALEXION PHARMACEUTICALS, INC. and Odyssey Merger Sub Inc.	05/07/2020
Merger agreement	Agreement and Plan of Merger, by and among Alexion, Beagle Merger Sub, Inc. and Achillion	10/16/2019
Merger agreement	Agreement and Plan of Merger, by and among Alexion, Beagle Merger Sub, Inc. and Achillion	10/16/2019