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PINNACLE ASSOCIATES LTD
> LXRX
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 12/31/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 1,932,777 | -98,430 | 3,691,604,000 | 3,686,729,000 | $1,910.00 |
| 09/30/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 2,031,207 | -56,256 | 4,875,000 | 992,000 | $2.40 |
| 06/30/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 2,087,463 | -6,831 | 3,883,000 | -494,000 | $1.86 |
| 03/31/2022 | LEXICON PHARMACEUTICALS, INC. | LXRX | 2,094,294 | -33,368 | 4,377,000 | -4,006,000 | $2.09 |
| 12/31/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 2,127,662 | 30,015 | 8,383,000 | -1,707,000 | $3.94 |
| 09/30/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 2,097,647 | -93,135 | 10,090,000 | 34,000 | $4.81 |
| 06/30/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 2,190,782 | 23,610 | 10,056,000 | -2,665,000 | $4.59 |
| 03/31/2021 | LEXICON PHARMACEUTICALS, INC. | LXRX | 2,167,172 | 1,819,912 | 12,721,000 | 12,221,000 | $5.87 |
| 09/30/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 347,260 | -11,250 | 500,000 | -215,000 | $1.44 |
| 06/30/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 358,510 | 2,165 | 715,000 | 20,000 | $1.99 |
| 03/31/2020 | LEXICON PHARMACEUTICALS, INC. | LXRX | 356,345 | -43,029 | 695,000 | -962,000 | $1.95 |
| 12/31/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 399,374 | -71,975 | 1,657,000 | 238,000 | $4.15 |
| 09/30/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 471,349 | -39,485 | 1,419,000 | -1,794,000 | $3.01 |
| 06/30/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 510,834 | -39,715 | 3,213,000 | 152,000 | $6.29 |
| 03/31/2019 | LEXICON PHARMACEUTICALS, INC. | LXRX | 550,549 | 9,615 | 3,061,000 | -531,000 | $5.56 |
| 12/31/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 540,934 | -37,785 | 3,592,000 | -2,583,000 | $6.64 |
| 09/30/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 578,719 | -96,106 | 6,175,000 | -1,923,000 | $10.67 |
| 06/30/2018 | LEXICON PHARMACEUTICALS, INC. | LXRX | 674,825 | -179,350 | 8,098,000 | -341,000 | $12.00 |
| 12/31/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 854,175 | -42,870 | 8,439,000 | -2,586,000 | $9.88 |
| 09/30/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 897,045 | 182,215 | 11,025,000 | -734,000 | $12.29 |
| 06/30/2017 | LEXICON PHARMACEUTICALS, INC. | LXRX | 714,830 | 714,830 | 11,759,000 | 11,759,000 | $16.45 |
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