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Cubist Systematic Strategies, LLC
> CARA
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Cara Therapeutics, Inc. | CARA | 184,604 | 184,604 | 522,429,000 | 522,429,000 | $2,830.00 |
| 09/30/2022 | Cara Therapeutics, Inc. | CARA | 0 | -277,887 | 0 | -2,537,000 | |
| 06/30/2022 | Cara Therapeutics, Inc. | CARA | 277,887 | 274,869 | 2,537,000 | 2,500,000 | $9.13 |
| 03/31/2022 | Cara Therapeutics, Inc. | CARA | 3,018 | -106,067 | 37,000 | -1,292,000 | $12.26 |
| 12/31/2021 | Cara Therapeutics, Inc. | CARA | 109,085 | 109,085 | 1,329,000 | 1,329,000 | $12.18 |
| 06/30/2021 | Cara Therapeutics, Inc. | CARA | 0 | -40,939 | 0 | -619,000 | |
| 12/31/2020 | Cara Therapeutics, Inc. | CARA | 40,939 | -28,287 | 619,000 | -262,000 | $15.12 |
| 09/30/2020 | Cara Therapeutics, Inc. | CARA | 69,226 | 20,111 | 881,000 | 41,000 | $12.73 |
| 06/30/2020 | Cara Therapeutics, Inc. | CARA | 49,115 | 38,805 | 840,000 | 704,000 | $17.10 |
| 03/31/2020 | Cara Therapeutics, Inc. | CARA | 10,310 | -47,925 | 136,000 | -802,000 | $13.19 |
| 12/31/2019 | Cara Therapeutics, Inc. | CARA | 58,235 | 45,535 | 938,000 | 706,000 | $16.11 |
| 09/30/2019 | Cara Therapeutics, Inc. | CARA | 12,700 | 12,700 | 232,000 | 232,000 | $18.27 |
| 06/30/2019 | Cara Therapeutics, Inc. | CARA | 0 | -2,105 | 0 | -41,000 | |
| 03/31/2019 | Cara Therapeutics, Inc. | CARA | 2,105 | -37,942 | 41,000 | -480,000 | $19.48 |
| 12/31/2018 | Cara Therapeutics, Inc. | CARA | 40,047 | 40,047 | 521,000 | 521,000 | $13.01 |
| 03/31/2017 | Cara Therapeutics, Inc. | CARA | 0 | -1,997 | 0 | -19,000 | |
| 12/31/2016 | Cara Therapeutics, Inc. | CARA | 1,997 | 1,725 | 19,000 | 17,000 | $9.51 |
| 09/30/2016 | Cara Therapeutics, Inc. | CARA | 272 | 272 | 2,000 | 2,000 | $7.35 |
| 06/30/2016 | Cara Therapeutics, Inc. | CARA | 0 | -15,820 | 0 | -226,000 | |
| 03/31/2016 | Cara Therapeutics, Inc. | CARA | 0 | -1,640 | 0 | -28,000 | |
| 12/31/2015 | Cara Therapeutics, Inc. | CARA | 1,640 | -14,180 | 28,000 | -198,000 | $17.07 |
| 09/30/2015 | Cara Therapeutics, Inc. | CARA | 15,820 | 15,820 | 226,000 | 226,000 | $14.29 |
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