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VANGUARD GROUP INC
> SPRB
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | SPRUCE BIOSCIENCES, INC. | SPRB | 261,954 | 136,975 | 563,202,000 | 563,031,000 | $2,150.00 |
| 09/30/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 124,979 | 8,921 | 171,000 | -31,000 | $1.37 |
| 06/30/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 116,058 | -37,678 | 202,000 | -107,000 | $1.74 |
| 03/31/2022 | SPRUCE BIOSCIENCES, INC. | SPRB | 153,736 | -218,391 | 309,000 | -1,351,000 | $2.01 |
| 12/31/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 372,127 | 1,277 | 1,660,000 | -569,000 | $4.46 |
| 09/30/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 370,850 | 1,330 | 2,229,000 | -1,913,000 | $6.01 |
| 06/30/2021 | SPRUCE BIOSCIENCES, INC. | SPRB | 369,520 | 185,462 | 4,142,000 | -332,000 | $11.21 |
| 12/31/2020 | SPRUCE BIOSCIENCES, INC. | SPRB | 184,058 | 184,058 | 4,474,000 | 4,474,000 | $24.31 |
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