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EDMOND DE ROTHSCHILD HOLDING S.A.
> AMGN
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | AMGEN INC | AMGN | 73,749 | -3,532 | 16,373,754,000 | -2,308,928,000 | $222,020.01 |
| 03/31/2023 | AMGEN INC | AMGN | 77,281 | -45,094 | 18,682,682,000 | 18,655,099,000 | $241,750.00 |
| 09/30/2022 | AMGEN INC | AMGN | 122,375 | -3,296 | 27,583,000 | -2,993,000 | $225.40 |
| 06/30/2022 | AMGEN INC | AMGN | 125,671 | -47,854 | 30,576,000 | -11,386,000 | $243.30 |
| 03/31/2022 | AMGEN INC | AMGN | 173,525 | 6,155 | 41,962,000 | 4,308,000 | $241.82 |
| 12/31/2021 | AMGEN INC | AMGN | 167,370 | -10,075 | 37,654,000 | -80,000 | $224.97 |
| 09/30/2021 | AMGEN INC | AMGN | 177,445 | 106,836 | 37,734,000 | 21,500,000 | $212.65 |
| 12/31/2020 | AMGEN INC | AMGN | 70,609 | 7,809 | 16,234,000 | 273,000 | $229.91 |
| 09/30/2020 | AMGEN INC | AMGN | 62,800 | -32,570 | 15,961,000 | -6,533,000 | $254.16 |
| 06/30/2020 | AMGEN INC | AMGN | 95,370 | 33,013 | 22,494,000 | 9,853,000 | $235.86 |
| 03/31/2020 | AMGEN INC | AMGN | 62,357 | -2,109 | 12,641,000 | -2,900,000 | $202.72 |
| 12/31/2019 | AMGEN INC | AMGN | 64,466 | -4,166 | 15,541,000 | 2,260,000 | $241.07 |
| 09/30/2019 | AMGEN INC | AMGN | 68,632 | 22,153 | 13,281,000 | 4,715,000 | $193.51 |
| 06/30/2019 | AMGEN INC | AMGN | 46,479 | 30,010 | 8,566,000 | 5,437,000 | $184.30 |
| 03/31/2019 | AMGEN INC | AMGN | 16,469 | 1 | 3,129,000 | -76,000 | $189.99 |
| 12/31/2018 | AMGEN INC | AMGN | 16,468 | -200 | 3,205,000 | -250,000 | $194.62 |
| 09/30/2018 | AMGEN INC | AMGN | 16,668 | -136 | 3,455,000 | 352,000 | $207.28 |
| 06/30/2018 | AMGEN INC | AMGN | 16,804 | 400 | 3,103,000 | 307,000 | $184.66 |
| 03/31/2018 | AMGEN INC | AMGN | 16,404 | -7,920 | 2,796,000 | -1,434,000 | $170.45 |
| 12/31/2017 | AMGEN INC | AMGN | 24,324 | -2,601 | 4,230,000 | -790,000 | $173.90 |
| 09/30/2017 | AMGEN INC | AMGN | 26,925 | 303 | 5,020,000 | 435,000 | $186.44 |
| 06/30/2017 | AMGEN INC | AMGN | 26,622 | -91,843 | 4,585,000 | -14,851,000 | $172.23 |
| 03/31/2017 | AMGEN INC | AMGN | 118,465 | 1,553 | 19,436,000 | 2,342,000 | $164.07 |
| 12/31/2016 | AMGEN INC | AMGN | 116,912 | 7,392 | 17,094,000 | -1,175,000 | $146.21 |
| 09/30/2016 | AMGEN INC | AMGN | 109,520 | 12,928 | 18,269,000 | 3,573,000 | $166.81 |
| 06/30/2016 | AMGEN INC | AMGN | 96,592 | 96,592 | 14,696,000 | 14,696,000 | $152.15 |
| 03/31/2016 | AMGEN INC | AMGN | 106,292 | 106,292 | 15,936,000 | 15,936,000 | $149.93 |
| 12/31/2015 | AMGEN INC | AMGN | 106,292 | 106,292 | 17,254,000 | 17,254,000 | $162.33 |
| 09/30/2015 | AMGEN INC | AMGN | 112,692 | 112,692 | 15,588,000 | 15,588,000 | $138.32 |
| 06/30/2015 | AMGEN INC | AMGN | 111,299 | 111,299 | 17,087,000 | 17,087,000 | $153.52 |
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