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ROCKEFELLER FINANCIAL SERVICES INC
> SHPG
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 12/31/2017 | Shire plc | SHPG | 578,215 | -11,685 | 89,693,000 | -644,000 | $155.12 |
| 09/30/2017 | Shire plc | SHPG | 589,900 | -78,249 | 90,337,000 | 90,226,574 | $153.14 |
| 06/30/2017 | Shire plc | SHPG | 668,149 | -10,621 | 110,426 | -7,836 | $0.17 |
| 03/31/2017 | Shire plc | SHPG | 678,770 | 1,206 | 118,262 | -115,324,738 | $0.17 |
| 12/31/2016 | Shire plc | SHPG | 677,564 | 91,230 | 115,443,000 | 1,776,000 | $170.38 |
| 09/30/2016 | Shire plc | SHPG | 586,334 | -28,980 | 113,667,000 | 401,000 | $193.86 |
| 06/30/2016 | Shire plc | SHPG | 615,314 | 361,743 | 113,266,000 | 69,677,000 | $184.08 |
| 03/31/2016 | Shire plc | SHPG | 253,571 | 248,809 | 43,589,000 | 43,018,000 | $171.90 |
| 12/31/2015 | Shire plc | SHPG | 2,366 | 2,304 | 485,000 | 472,000 | $204.99 |
| 09/30/2015 | Shire plc | SHPG | 62 | -4,700 | 13,000 | -558,000 | $209.68 |
| 06/30/2015 | Shire plc | SHPG | 62 | 0 | 15,000 | 0 | $241.94 |
| 03/31/2015 | Shire plc | SHPG | 62 | 0 | 15,000 | -1,000 | $241.94 |
| 12/31/2014 | Shire plc | SHPG | 202 | 140 | 43,000 | 27,000 | $212.87 |
| 09/30/2014 | Shire plc | SHPG | 62 | -4,700 | 16,000 | -555,000 | $258.06 |
| 06/30/2014 | Shire plc | SHPG | 3,019 | 0 | 711,000 | 263,000 | $235.51 |
| 03/31/2014 | Shire plc | SHPG | 3,019 | -1,743 | 448,000 | -123,000 | $148.39 |
| 12/31/2013 | Shire plc | SHPG | 3,101 | -1,661 | 438,000 | -133,000 | $141.24 |
| 09/30/2013 | Shire plc | SHPG | 4,762 | 431 | 571,000 | 159,000 | $119.91 |
| 06/30/2013 | Shire plc | SHPG | 4,331 | 609 | 412,000 | 72,000 | $95.13 |
| 03/31/2013 | Shire plc | SHPG | 3,722 | 1,430 | 340,000 | 129,000 | $91.35 |
| 12/31/2012 | Shire plc | SHPG | 2,292 | 350 | 211,000 | 39,000 | $92.06 |
| 09/30/2012 | Shire plc | SHPG | 1,942 | 1,942 | 172,000 | 172,000 | $88.57 |
| 06/30/2012 | Shire plc | SHPG | 0 | -1,942 | 0 | -184,000 | |
| 03/31/2012 | Shire plc | SHPG | 1,942 | -1,220 | 184,000 | -113,000 | $94.75 |
| 12/31/2011 | Shire plc | SHPG | 2,852 | -310 | 296,000 | -1,000 | $103.79 |
| 09/30/2011 | Shire plc | SHPG | 3,162 | -3,702 | 297,000 | -349,000 | $93.93 |
| 06/30/2011 | Shire plc | SHPG | 6,864 | -3,710 | 646,000 | -274,000 | $94.11 |
| 03/31/2011 | Shire plc | SHPG | 10,574 | 9,306 | 920,000 | 828,000 | $87.01 |
| 12/31/2010 | Shire plc | SHPG | 1,268 | -15,559 | 92,000 | -1,040,000 | $72.56 |
| 09/30/2010 | Shire plc | SHPG | 16,827 | 16,730 | 1,132,000 | 1,126,000 | $67.27 |
| 06/30/2010 | Shire plc | SHPG | 97 | 0 | 6,000 | 0 | $61.86 |
| 03/31/2010 | Shire plc | SHPG | 97 | -35,863 | 6,000 | -2,105,000 | $61.86 |
| 12/31/2009 | Shire plc | SHPG | 35,960 | 0 | 2,111,000 | 231,000 | $58.70 |
| 09/30/2009 | Shire plc | SHPG | 35,960 | 35,960 | 1,880,000 | 1,880,000 | $52.28 |
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