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ADAGE CAPITAL PARTNERS GP, L.L.C.
> ISEE
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | IVERIC bio, Inc. | ISEE | 1,163,140 | 1,084,140 | 45,757,928,000 | 43,835,858,000 | $39,340.00 |
| 03/31/2023 | IVERIC bio, Inc. | ISEE | 79,000 | -771,000 | 1,922,070,000 | 1,906,821,000 | $24,330.00 |
| 09/30/2022 | IVERIC bio, Inc. | ISEE | 850,000 | 630,000 | 15,249,000 | 13,133,000 | $17.94 |
| 06/30/2022 | IVERIC bio, Inc. | ISEE | 220,000 | -280,000 | 2,116,000 | -6,299,000 | $9.62 |
| 03/31/2022 | IVERIC bio, Inc. | ISEE | 500,000 | 500,000 | 8,415,000 | 8,415,000 | $16.83 |
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