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MILLENNIUM MANAGEMENT LLC
> BCYC
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | BICYCLE THERAPEUTICS plc | BCYC | 78,759 | -89,964 | 2,009,930,000 | 2,004,936,000 | $25,520.00 |
| 12/31/2022 | BICYCLE THERAPEUTICS plc | BCYC | 168,723 | 25,677 | 4,994,000 | 1,667,000 | $29.60 |
| 09/30/2022 | BICYCLE THERAPEUTICS plc | BCYC | 143,046 | -190,655 | 3,327,000 | -2,273,000 | $23.26 |
| 06/30/2022 | BICYCLE THERAPEUTICS plc | BCYC | 333,701 | 170,334 | 5,600,000 | -1,569,000 | $16.78 |
| 03/31/2022 | BICYCLE THERAPEUTICS plc | BCYC | 163,367 | 10,635 | 7,169,000 | -2,128,000 | $43.88 |
| 12/31/2021 | BICYCLE THERAPEUTICS plc | BCYC | 152,732 | 152,732 | 9,297,000 | 9,297,000 | $60.87 |
| 09/30/2021 | BICYCLE THERAPEUTICS plc | BCYC | 0 | -20,363 | 0 | -618,000 | |
| 06/30/2021 | BICYCLE THERAPEUTICS plc | BCYC | 20,363 | 20,363 | 618,000 | 618,000 | $30.35 |
| 03/31/2021 | BICYCLE THERAPEUTICS plc | BCYC | 0 | -14,442 | 0 | -259,000 | |
| 12/31/2020 | BICYCLE THERAPEUTICS plc | BCYC | 14,442 | -3,872 | 259,000 | -25,000 | $17.93 |
| 06/30/2020 | BICYCLE THERAPEUTICS plc | BCYC | 18,314 | 3,073 | 284,000 | 56,000 | $15.51 |
| 03/31/2020 | BICYCLE THERAPEUTICS plc | BCYC | 15,241 | -5,949 | 228,000 | 28,000 | $14.96 |
| 12/31/2019 | BICYCLE THERAPEUTICS plc | BCYC | 21,190 | -13,579 | 200,000 | -196,000 | $9.44 |
| 09/30/2019 | BICYCLE THERAPEUTICS plc | BCYC | 34,769 | -18,591 | 396,000 | -141,000 | $11.39 |
| 06/30/2019 | BICYCLE THERAPEUTICS plc | BCYC | 53,360 | 53,360 | 537,000 | 537,000 | $10.06 |
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