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NORTHERN TRUST CORP
> ZYNE
| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | Zynerba Pharmaceuticals, Inc. | ZYNE | 115,210 | 0 | 37,559,000 | -11,981,000 | $326.00 |
| 03/31/2023 | Zynerba Pharmaceuticals, Inc. | ZYNE | 115,210 | -1,547 | 49,540,000 | 49,455,000 | $430.00 |
| 09/30/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | 116,757 | 1,775 | 85,000 | -46,000 | $0.73 |
| 06/30/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | 114,982 | -227 | 131,000 | -105,000 | $1.14 |
| 03/31/2022 | Zynerba Pharmaceuticals, Inc. | ZYNE | 115,209 | -5,260 | 236,000 | -111,000 | $2.05 |
| 12/31/2021 | Zynerba Pharmaceuticals, Inc. | ZYNE | 120,469 | -17,235 | 347,000 | -237,000 | $2.88 |
| 09/30/2021 | Zynerba Pharmaceuticals, Inc. | ZYNE | 137,704 | 16,960 | 584,000 | -55,000 | $4.24 |
| 06/30/2021 | Zynerba Pharmaceuticals, Inc. | ZYNE | 120,744 | -3,992 | 639,000 | 227,000 | $5.29 |
| 12/31/2020 | Zynerba Pharmaceuticals, Inc. | ZYNE | 124,736 | -14,123 | 412,000 | -48,000 | $3.30 |
| 09/30/2020 | Zynerba Pharmaceuticals, Inc. | ZYNE | 138,859 | -190,522 | 460,000 | -801,000 | $3.31 |
| 03/31/2020 | Zynerba Pharmaceuticals, Inc. | ZYNE | 329,381 | 13,307 | 1,261,000 | -648,000 | $3.83 |
| 12/31/2019 | Zynerba Pharmaceuticals, Inc. | ZYNE | 316,074 | 999 | 1,909,000 | -473,000 | $6.04 |
| 09/30/2019 | Zynerba Pharmaceuticals, Inc. | ZYNE | 315,075 | 215,577 | 2,382,000 | 1,034,000 | $7.56 |
| 06/30/2019 | Zynerba Pharmaceuticals, Inc. | ZYNE | 99,498 | 26,502 | 1,348,000 | 953,000 | $13.55 |
| 03/31/2019 | Zynerba Pharmaceuticals, Inc. | ZYNE | 72,996 | -13,959 | 395,000 | 137,000 | $5.41 |
| 12/31/2018 | Zynerba Pharmaceuticals, Inc. | ZYNE | 86,955 | -8,247 | 258,000 | -518,000 | $2.97 |
| 09/30/2018 | Zynerba Pharmaceuticals, Inc. | ZYNE | 95,202 | 32,461 | 776,000 | 164,000 | $8.15 |
| 06/30/2018 | Zynerba Pharmaceuticals, Inc. | ZYNE | 62,741 | -104,601 | 612,000 | -843,000 | $9.75 |
| 03/31/2018 | Zynerba Pharmaceuticals, Inc. | ZYNE | 167,342 | 24,663 | 1,455,000 | -331,000 | $8.69 |
| 12/31/2017 | Zynerba Pharmaceuticals, Inc. | ZYNE | 142,679 | 6,787 | 1,786,000 | 650,000 | $12.52 |
| 09/30/2017 | Zynerba Pharmaceuticals, Inc. | ZYNE | 135,892 | 16 | 1,136,000 | -1,170,000 | $8.36 |
| 06/30/2017 | Zynerba Pharmaceuticals, Inc. | ZYNE | 135,876 | 109,770 | 2,306,000 | 1,781,000 | $16.97 |
| 03/31/2017 | Zynerba Pharmaceuticals, Inc. | ZYNE | 26,106 | 26,106 | 525,000 | 525,000 | $20.11 |
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