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CLOUGH CAPITAL PARTNERS L P > BSMD

DateNameTickerSharesChangeValueChangePrice
03/31/2010BIOSPHERE MEDICAL INCBSMD1,226,312-79,9843,167,000-412,000$2.58
12/31/2009BIOSPHERE MEDICAL INCBSMD1,306,2967,8003,579,000-849,000$2.74
09/30/2009BIOSPHERE MEDICAL INCBSMD1,298,49694,4004,428,0001,550,000$3.41
06/30/2009BIOSPHERE MEDICAL INCBSMD1,204,096-37,9002,878,000394,000$2.39
03/31/2009BIOSPHERE MEDICAL INCBSMD1,241,996-14,0002,484,00060,000$2.00
12/31/2008BIOSPHERE MEDICAL INCBSMD1,255,99602,424,000-1,992,000$1.93
09/30/2008BIOSPHERE MEDICAL INCBSMD1,255,996-10,7004,416,00048,000$3.52
06/30/2008BIOSPHERE MEDICAL INCBSMD1,266,6968,4004,368,000-1,408,000$3.45
03/31/2008BIOSPHERE MEDICAL INCBSMD1,258,296-47,0005,776,000-920,000$4.59
12/31/2007BIOSPHERE MEDICAL INCBSMD1,305,2961,5006,696,000468,000$5.13
09/30/2007BIOSPHERE MEDICAL INCBSMD1,303,79650,0006,228,000-2,636,000$4.78
06/30/2007BIOSPHERE MEDICAL INCBSMD1,253,7961,253,7968,864,0008,864,000$7.07
03/31/2007BIOSPHERE MEDICAL INCBSMD1,253,79609,219,000844,000$7.35
12/31/2006BIOSPHERE MEDICAL INCBSMD1,253,7965,5008,375,000563,000$6.68
09/30/2006BIOSPHERE MEDICAL INCBSMD1,248,29617,9007,812,000-1,000$6.26
06/30/2006BIOSPHERE MEDICAL INCBSMD1,230,39663,6007,813,000-938,000$6.35
03/31/2006BIOSPHERE MEDICAL INCBSMD1,166,79620,0008,751,000-492,000$7.50
12/31/2005BIOSPHERE MEDICAL INCBSMD1,146,79666,1009,243,0003,119,000$8.06
09/30/2005BIOSPHERE MEDICAL INCBSMD1,080,69624,4256,124,0001,333,000$5.67
06/30/2005BIOSPHERE MEDICAL INCBSMD1,056,271158,0794,791,0001,246,000$4.54
03/31/2005BIOSPHERE MEDICAL INCBSMD898,192111,2003,545,000436,000$3.95
12/31/2004BIOSPHERE MEDICAL INCBSMD786,992187,6033,109,0001,143,000$3.95
09/30/2004BIOSPHERE MEDICAL INCBSMD599,38993,3041,966,000347,000$3.28
08/13/2004BIOSPHERE MEDICAL INCBSMD506,08520,6001,619,000-687,000$3.20
03/31/2004BIOSPHERE MEDICAL INCBSMD485,485105,8002,306,000806,000$4.75
12/31/2003BIOSPHERE MEDICAL INCBSMD379,685379,6851,500,0001,500,000$3.95
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