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CITADEL ADVISORS LLC
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| Date | Name | Ticker | Shares | Change | Value | Change | Price |
| 06/30/2023 | 89bio, Inc. | ETNB | 1,084,356 | 134,044 | 20,548,546,000 | 8,451,074,000 | $18,950.00 |
| 12/31/2022 | 89bio, Inc. | ETNB | 950,312 | -184,110 | 12,097,472,000 | 12,090,904,000 | $12,730.00 |
| 09/30/2022 | 89bio, Inc. | ETNB | 1,134,422 | 70,818 | 6,568,000 | 3,144,000 | $5.79 |
| 06/30/2022 | 89bio, Inc. | ETNB | 1,063,604 | 650,485 | 3,424,000 | 1,866,000 | $3.22 |
| 03/31/2022 | 89bio, Inc. | ETNB | 413,119 | 142,715 | 1,558,000 | -1,976,000 | $3.77 |
| 12/31/2021 | 89bio, Inc. | ETNB | 270,404 | -19,450 | 3,534,000 | -2,144,000 | $13.07 |
| 09/30/2021 | 89bio, Inc. | ETNB | 289,854 | -198,911 | 5,678,000 | -3,462,000 | $19.59 |
| 06/30/2021 | 89bio, Inc. | ETNB | 488,765 | -19,102 | 9,140,000 | -2,886,000 | $18.70 |
| 03/31/2021 | 89bio, Inc. | ETNB | 507,867 | 17,914 | 12,026,000 | 86,000 | $23.68 |
| 12/31/2020 | 89bio, Inc. | ETNB | 489,953 | 480,519 | 11,940,000 | 11,698,000 | $24.37 |
| 09/30/2020 | 89bio, Inc. | ETNB | 9,434 | 9,434 | 242,000 | 242,000 | $25.65 |
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