Prime Medicine, Inc. [Rocket]

Ownership

Prime Medicine, Inc.

Portfolio as of:

Name	Shares	Change	Value	% Port	% OS	Hist	Date
Alphabet Inc.	13,284,688	0	163,401,662,000	9.06	13.66	Hist	03/31/2023
FMR LLC	4,039,219	-4,477,910	59,174,558,000	0.00	4.15	Hist	06/30/2023
VANGUARD GROUP INC	3,334,483	3,334,483	48,850,175,000	0.00	3.43	Hist	06/30/2023
Nikko Asset Management Americas, Inc.	3,064,616	2,065,283	44,804,686,000	0.47	3.15	Hist	06/30/2023
BlackRock Inc.	2,889,216	1,375,093	42,327,014,000	0.00	2.97	Hist	06/30/2023
ARK Investment Management LLC	2,449,199	2,449,199	35,880,771,000	0.24	2.52	Hist	06/30/2023
FIL Ltd	1,805,558	0	26,451,425,000	0.03	1.86	Hist	06/30/2023
MWG Management Ltd.	1,792,210	-43,666	26,255,877,000	15.88	1.84	Hist	06/30/2023
Redmile Group, LLC	1,324,350	-885,000	19,401,728,000	0.74	1.36	Hist	06/30/2023
BAKER BROS. ADVISORS LP	1,028,466	0	15,067,027,000	0.09	1.06	Hist	06/30/2023
DEERFIELD MANAGEMENT COMPANY, L.P. (SERIES C)	885,314	0	12,969,850,000	0.28	0.91	Hist	06/30/2023
STATE STREET CORP	605,199	490,353	8,866,165,000	0.00	0.62	Hist	06/30/2023
EcoR1 Capital, LLC	600,000	0	8,790,000,000	0.22	0.62	Hist	06/30/2023
JANUS HENDERSON GROUP PLC	564,854	564,854	8,269,464,000	0.01	0.58	Hist	06/30/2023
GEODE CAPITAL MANAGEMENT, LLC	540,308	299,963	7,915,512,000	0.00	0.56	Hist	06/30/2023
Samsara BioCapital, LLC	470,304	0	6,889,954,000	1.21	0.48	Hist	06/30/2023
MOORE CAPITAL MANAGEMENT, LP	446,733	-53,267	6,544,638,000	0.11	0.46	Hist	06/30/2023
JANE STREET GROUP, LLC	397,004	397,004	5,816,109,000	0.00	0.41	Hist	06/30/2023
Casdin Capital, LLC	367,175	-367,175	5,379,114,000	0.47	0.38	Hist	06/30/2023
NORTHERN TRUST CORP	282,431	192,352	4,137,615,000	0.00	0.29	Hist	06/30/2023
MILLENNIUM MANAGEMENT LLC	256,560	256,560	3,758,604,000	0.00	0.26	Hist	06/30/2023
Ensign Peak Advisors, Inc	150,000	0	2,197,500,000	0.00	0.15	Hist	06/30/2023
BANK OF AMERICA CORP /DE/	147,515	-2,752	2,161,094,000	0.00	0.15	Hist	06/30/2023
Nuveen Asset Management, LLC	123,195	109,067	1,804,807,000			Hist	06/30/2023
Bank of New York Mellon Corp	103,213	73,145	1,512,070,000	0.00	0.11	Hist	06/30/2023
UBS Group AG	99,039	94,104	1,450,921,000	0.00	0.10	Hist	06/30/2023
TD ASSET MANAGEMENT INC	67,071	43,149	982,590,000	0.00	0.07	Hist	06/30/2023
MANUFACTURERS LIFE INSURANCE COMPANY, THE	58,401	12,770	855,575,000	0.00	0.06	Hist	06/30/2023
MORGAN STANLEY	57,929	37,540	848,662,000	0.00	0.06	Hist	06/30/2023
Laurion Capital Management LP	55,888	-4,112	818,759,000	0.00	0.06	Hist	06/30/2023
RHUMBLINE ADVISERS	47,063	47,063	689,472,000	0.00	0.05	Hist	06/30/2023
BRANDYWINE MANAGERS, LLC	32,977	0	483,113,000	0.32	0.03	Hist	06/30/2023
JPMORGAN CHASE & CO	30,672	17,775	449,345,000	0.00	0.03	Hist	06/30/2023
ALLIANCEBERNSTEIN L.P.	26,540	26,540	388,811,000	0.00	0.03	Hist	06/30/2023
Green Alpha Advisors, LLC	37,815	25,429	360,755,000	0.28	0.04	Hist	09/30/2023
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