| Date | Name | Symbol | Type | Security | Shares | Price | Value | Ownership | Reported |
| 02/23/2023 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Restricted Stock Units | 5k | $0.00 | $0 | | 02/23/2023 |
| 02/23/2023 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Employee Stock Option (Right to Buy) | 20k | $38.60 | $772k | | 02/23/2023 |
| 02/22/2023 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Disposition | Restricted Stock Units | 750 | $0.00 | $0 | | 02/22/2023 |
| 02/22/2023 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Common Stock | 750 | $0.00 | $0 | | 02/22/2023 |
| 02/16/2023 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Exercise | Performance Share Unit | 1.5k | $0.00 | $0 | | 02/16/2023 |
| 08/22/2022 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Sale | Common Stock | 5k | $35.98 | $179.9k | | 08/22/2022 |
| 08/22/2022 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Exercise | Employee Stock Option (Right to Buy) | 5k | $7.90 | $39.5k | | 08/22/2022 |
| 08/04/2022 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Exercise | Employee Stock Option (Right to Buy) | 5k | $7.90 | $39.5k | | 08/04/2022 |
| 08/04/2022 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Sale | Common Stock | 5k | $32.98 | $164.9k | | 08/04/2022 |
| 02/22/2022 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Employee Stock Option (Right to Buy) | 18k | $32.20 | $579.6k | | 02/22/2022 |
| 02/22/2022 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Restricted Stock Units | 3k | $0.00 | $0 | | 02/22/2022 |
| 04/14/2021 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Exercise | Employee Stock Option (Right to Buy) | 3.1k | $12.98 | $40.6k | | 04/13/2021 |
| 04/14/2021 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Sale | Common Stock | 3.1k | $31.98 | $99.9k | | 04/13/2021 |
| 04/13/2021 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Sale | Common Stock | 3.1k | $29.98 | $93.7k | | 04/13/2021 |
| 04/13/2021 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Exercise | Employee Stock Option (Right to Buy) | 3.1k | $12.98 | $40.6k | | 04/13/2021 |
| 02/19/2021 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Employee Stock Option (Right to Buy) | 17k | $29.61 | $503.4k | | 02/19/2021 |
| 02/21/2020 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Grant | Employee Stock Option (Right to Buy) | 22k | $23.99 | $527.8k | | 02/21/2020 |
| 12/12/2012 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Exercise | Employee Stock Option (right to buy) | 9.4k | $2.56 | $24k | | 12/12/2012 |
| 12/12/2012 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Exercise | Employee Stock Option (right to buy) | 1.2k | $3.36 | $4.2k | | 12/12/2012 |
| 12/12/2012 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Exercise | Employee Stock Option (right to buy) | 37.5k | $1.60 | $60k | | 12/12/2012 |
| 05/04/2012 | SUPERNUS PHARMACEUTICALS, INC. | SUPN | Purchase | Common Stock | 2.5k | $5.00 | $12.5k | | 05/04/2012 |